中文题名 / Chinese title: 喙形态的细胞与分子起源
英文题名 / English title: The cellular and molecular origins of beak morphology.
作者 / Authors: Schneider RA, Helms JA.
期刊 / Journal: Science
年份 / Year: 2003
DOI: 10.1126/science.1077827
论文链接 / Article: https://doi.org/10.1126/science.1077827
摘要来源 / Abstract source: https://europepmc.org/article/MED/12543976

英文摘要原文 / Original English abstract
Cellular and molecular mechanisms underlying differences in beak morphology likely involve interactions among multiple embryonic populations. We exchanged neural crest cells destined to participate in beak morphogenesis between two anatomically distinct species. Quail neural crest cells produced quail beaks in duck hosts and duck neural crest produced duck bills in quail hosts. These transformations involved morphological changes to non-neural crest host beak tissues. To achieve these changes, donor neural crest cells executed autonomous molecular programs and regulated gene expression in adjacent host tissues. Thus, neural crest cells are a source of molecular information that generates interspecific variation in beak morphology.

摘要依据的主要发现 / Findings based on the abstract
在鸭与鹌鹑胚胎间交换神经嵴细胞，可使宿主形成类似供体的喙；供体细胞执行自身程序，并改变相邻宿主组织的基因表达。
Neural-crest exchanges between duck and quail embryos produced donor-like beaks in host embryos. Donor cells followed autonomous programs and altered gene expression in adjacent host tissues.

摘要依据的结论 / Conclusions based on the abstract
神经嵴细胞提供指导性信息，协调其他组织并促成物种特异的喙形差异。
Neural-crest cells supply instructive information that coordinates other tissues and contributes to species-specific beak variation.

可用全文文件 / Available full-text files